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Application of silicon nanowires and indium tin oxide surfaces in desorption electrospray ionization.

Identifieur interne : 002449 ( Main/Exploration ); précédent : 002448; suivant : 002450

Application of silicon nanowires and indium tin oxide surfaces in desorption electrospray ionization.

Auteurs : RBID : pubmed:19136727

English descriptors

Abstract

Two nanostructured surfaces are introduced as advantageous substrates for desorption electrospray ionization mass spectrometry (DESI-MS). Nano-assisted laser desorption/ionization (NALDI) plates coated with silicon nanowires (SiNWs) and indium tin oxide (ITO) layers on glass are both conductive non-polar surfaces that were originally designed as superior substrates for matrix-free laser desorption/ionization. In this study, NALDI/SiNWs and ITO were tested as potentially useful DESI substrates for selected model analytes (cyclosporine, beauverolide, surfactin and nystatin). Both nanostructured surfaces produced more intense and longer-lasting signals than other tested surfaces (polytetrafluoroethylene, glass, polymethylmethacrylate and chromatography paper).

DOI: 10.1255/ejms.961
PubMed: 19136727

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Le document en format XML

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<title xml:lang="en">Application of silicon nanowires and indium tin oxide surfaces in desorption electrospray ionization.</title>
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<name sortKey="P L, Jaroslav" uniqKey="P L J">Jaroslav Pól</name>
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<nlm:affiliation>Laboratory of Molecular Structure Characterization, Institute of Microbiology, Academy of Sciences of the Czech Republic. jaroslav.pol@helsinki.fi</nlm:affiliation>
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<name sortKey="Nov K, Petr" uniqKey="Nov K P">Petr Novák</name>
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<name sortKey="Voln, Michael" uniqKey="Voln M">Michael Volný</name>
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<name sortKey="Kruppa, Gary H" uniqKey="Kruppa G">Gary H Kruppa</name>
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<name sortKey="Kostiainen, Risto" uniqKey="Kostiainen R">Risto Kostiainen</name>
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<name sortKey="Lemr, Karel" uniqKey="Lemr K">Karel Lemr</name>
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<name sortKey="Havl Cek, Vladim R" uniqKey="Havl Cek V">Vladimír Havlícek</name>
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<term>Reproducibility of Results</term>
<term>Silicon (chemistry)</term>
<term>Spectrometry, Mass, Electrospray Ionization (methods)</term>
<term>Surface Properties</term>
<term>Tin Compounds (chemistry)</term>
<term>Uncertainty</term>
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<div type="abstract" xml:lang="en">Two nanostructured surfaces are introduced as advantageous substrates for desorption electrospray ionization mass spectrometry (DESI-MS). Nano-assisted laser desorption/ionization (NALDI) plates coated with silicon nanowires (SiNWs) and indium tin oxide (ITO) layers on glass are both conductive non-polar surfaces that were originally designed as superior substrates for matrix-free laser desorption/ionization. In this study, NALDI/SiNWs and ITO were tested as potentially useful DESI substrates for selected model analytes (cyclosporine, beauverolide, surfactin and nystatin). Both nanostructured surfaces produced more intense and longer-lasting signals than other tested surfaces (polytetrafluoroethylene, glass, polymethylmethacrylate and chromatography paper).</div>
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<Title>European journal of mass spectrometry (Chichester, England)</Title>
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